Likelihood of progression to severe disease

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This table shows the prevalence of each symptom below in patients hospitalised with COVID 19.  It will help you understand the evidence for how strongly each symptom is associated with progression to severe disease.

See the table in the full review here

Cough

Cough 

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised

ISARIC, 202112

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

49.3

68.9

64.1

56.0

 

Cough (sputum)

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised

ISARIC, 202112

Docherty et al, 20209

Anderson et al, 20215

Mair et al,

20218 

 
- 26.2 - -

Cough (blood)

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 
-

3.5

- 

- 

Fever > 37.8 C

Fever > 37.8°C

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

46.8

71.6

 77.5 75

 

Dyspnoea

Dyspnoea/shortness of breath

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 
 51.0

71.2

22.2

22.0

 

Fatigue

Fatigue/malaise

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

Docherty et al, 20209

Anderson et al, 20215

Mair et al,

20218 

 
30.1 45.5 34.1 35

 

Delirium (confusion)

Delirium (confusion)

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised

 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

16.3

 26.7 - -

Consider COVID-19 when assessing frail elderly patients with delirium, even if other symptoms might not be typical of COVID-19.15,16

 

Diarrhoea

Diarrhoea

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 12.8

20.4

9.4

10.0

 

Vomiting/nausea

Vomiting/nausea

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 13.4

19.8

 - 8.0

 

Myalgia/muscle ache

Myalgia/muscle ache

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 -

20.6

20.3

-

 

Chest pain

Chest pain

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 10.1

14.6 

- 

- 

 

Headache

Headache

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 7.9

12.5 

8.7 

 14.0

Abdominal pain

Abdominal pain

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

Anderson et al, 20215

 

Mair et al,

20218 

 

7.0

10.2

 -

 -

 

Sore throat

Sore throat

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

5.2

 9.8 12.7

17.0 

Loss/altered sense of taste

Loss/altered sense of taste

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 4.4

-

-

21.0 

Loss/altered sense of smell

Loss/altered sense of smell

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

 3.7

-

- 

42.0 

Wheeze

Wheeze

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

4.6

10.9

- 

- 

Joint pain

Joint pain

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 

-

7.5

- 

- 

Severe dehydration

Severe dehydration

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 
4.5

-

- 

- 

Runny nose

Runny nose

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218 

 
2.3 3.6

5.5 

8.0 

Skin rash/skin ulcers

Skin rash/skin ulcers

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

 

Docherty et al, 20209

 

Anderson et al, 20215

 

Mair et al,

20218

 
2.0 2.0

- 

- 

Muscle ache/joint pain

Muscle ache/joint pain

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

Docherty et al, 20209

Anderson et al, 20215

Mair et al,

20218 

 
13.1 - - -

Anorexia

Anorexia

Prevalence of symptoms in COVID 19 patients COVID-19: % of patients hospitalised


 

ISARIC, 202112

Docherty et al, 20209

Anderson et al, 20215

Mair et al,
- - 19.4 -